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TMS for Older Adults: Safety, Medicare and Results

TMS is a good fit for older adults with depression, and Medicare pays for it. Late-life depression responds to TMS in controlled trials, there is no upper age limit, the treatment has no drug interactions and no sedation, and it causes no cognitive side effects, which matters for anyone worried about memory. For a patient in their seventies on eight other medications who has not tolerated two antidepressants, TMS is often the cleanest option on the table.

The short answer

TMS is effective and safe for older adults with depression, with no upper age limit, no drug interactions and no cognitive side effects. Medicare covers it in Florida and South Carolina once a psychiatrist documents the diagnosis and one failed antidepressant trial. Deep TMS produced remission in 40 percent of patients aged 60 to 85 in a controlled trial.

The questions older patients and their families ask are practical: does it work as well at 75 as at 40, is it safe with a pacemaker or after a stroke, what exactly does Medicare require, and how does someone in assisted living get to daily sessions for six weeks. This page answers each, including how our Stedfast Living program coordinates TMS for residents of senior facilities.

Who it is for

The typical older candidate is an adult of 60 or older with major depressive disorder that has not responded to at least one antidepressant, or who could not tolerate the medication. That describes a large share of late-life depression: older adults are more sensitive to antidepressant side effects, including falls, low sodium, bleeding risk with blood thinners and interactions with cardiac medications, and many stop treatment early. TMS sidesteps all of that. It is particularly worth considering for patients with multiple medical conditions and a long medication list, for those with early memory concerns who want to avoid anticholinergic or sedating drugs, for patients who have had depression before and responded to treatment, and for residents of assisted living, independent living and skilled nursing facilities who are seen through our Stedfast Living program. Patients with dementia-related depression are evaluated case by case; TMS is not a treatment for dementia itself.

How it works

Deep TMS uses a helmet-mounted coil to deliver magnetic pulses to the prefrontal cortex, which regulates mood and is underactive in depression at any age. The mechanism is the same in older adults, with one practical wrinkle. Normal aging thins the cortex and widens the space between the skull and the brain, so a given pulse reaches the target with less strength. Early studies with handheld figure-8 coils found weaker results in older patients and blamed this distance. Two things changed the picture: stimulation intensity was raised to compensate, and Deep TMS coils, which reach further, were developed. Trials in patients up to 85 and beyond now show response rates comparable to younger adults. The dose is individualized for every patient at the first session by finding the motor threshold, the intensity that makes the thumb twitch, so age-related differences are measured rather than guessed.

In a randomized sham-controlled trial of Deep TMS in 52 patients aged 60 to 85 with treatment-resistant depression, four weeks of daily treatment produced remission in 40 percent of the active group versus 14.8 percent with sham.

Source: Kaster et al., Neuropsychopharmacology, 2018

In a randomized trial of 172 adults aged 60 and older with treatment-resistant depression, theta burst stimulation was non-inferior to standard bilateral TMS, with remission rates of about 35 percent and 33 percent respectively.

Source: Blumberger et al., JAMA Psychiatry, 2022 (FOUR-D trial)

Major depression affects an estimated 1 to 5 percent of community-dwelling older adults, rising to 11.5 percent of hospitalized older patients and 13.5 percent of those requiring home health care.

Source: Centers for Disease Control and Prevention

The Florida Medicare local coverage determination for TMS requires a documented diagnosis of major depressive disorder, failure of or intolerance to at least one antidepressant trial, and an order from a psychiatrist after a face-to-face evaluation.

Source: First Coast Service Options, LCD L34522

What to expect

The evaluation takes place at any of our 13 offices, by video, or for facility residents, at the facility through Stedfast Living. A psychiatrist confirms the diagnosis, reviews medications and medical history, scores the PHQ-9 and often the Geriatric Depression Scale, and checks for contraindications, with specific attention to implanted devices, stroke history and seizure risk. Medicare requires that a psychiatrist see you in person before ordering TMS, so at least one visit is face to face. Treatment sessions take place at our TMS treatment centers, with Palm Beach Gardens as the primary center: 36 sessions of about 20 minutes over about nine weeks. You can drive yourself, be driven, or use facility transport. There is no sedation and nothing to recover from. Family members are welcome to sit in on the first session.

Benefits

  • Covered by Medicare Part B in Florida and South Carolina, with no upper age limit
  • No drug interactions, which matters for patients on anticoagulants, cardiac and diabetes medications
  • No sedation, no fall risk and no cognitive side effects, unlike many antidepressants in older adults
  • Remission rates in controlled trials of patients 60 and older comparable to younger adults
  • Evaluation available at the office, by video or at senior living facilities through Stedfast Living
  • Repeat courses covered by Medicare for patients who responded before

Risks and side effects

Older patients experience the same side effects as younger ones: scalp discomfort and headache in the first week, which usually resolve, and a rare seizure risk of roughly one in 30,000 sessions. A few considerations are more common with age. Pacemakers and implanted defibrillators are a relative contraindication: at chest distance from the coil they are usually acceptable with cardiology clearance and confirmation of the device model. Prior stroke raises seizure risk and requires review of imaging; many stroke survivors are treated safely. Hearing protection is provided because the coil clicks loudly, and hearing aids are removed during sessions. Medications that lower the seizure threshold, such as tramadol and bupropion above 300 mg, are reviewed. Dental work, hip and knee replacements and most surgical hardware are not a concern.

Cost and insurance

Medicare covers TMS for major depressive disorder under local coverage determinations: First Coast Service Options in Florida and Palmetto GBA in South Carolina. The requirements are a confirmed diagnosis of major depressive disorder documented with a standardized rating scale, failure of or intolerance to at least one antidepressant trial of adequate dose and duration, and an order from a psychiatrist who has evaluated you in person. There is no national coverage determination, so the local rules apply. Medicare pays 80 percent of the allowed amount after the Part B deductible; a Medigap supplement typically covers the remaining 20 percent. Medicare Advantage plans cover TMS but require prior authorization and may add their own criteria. Our TMS coordinator handles the documentation and tells you your expected cost before you begin.

Why late-life depression is undertreated

Depression in older adults is often missed, dismissed as a normal part of aging, or treated with medications that cause more trouble than they are worth. Antidepressants in seniors carry real hazards: SSRIs raise fall risk and can drop sodium levels, tricyclics cause confusion and cardiac effects, and nearly every option interacts with something on a typical eight-drug list. Many older patients try one antidepressant, stop it because of side effects, and conclude that treatment is not for them.

TMS changes that calculation. Nothing enters the bloodstream, nothing interacts with warfarin or metoprolol or metformin, nothing sedates, and nothing clouds memory. The question is whether it works in older brains, and the trials now say it does.

The evidence in older adults

The early concern

Studies in the late 1990s and early 2000s with handheld figure-8 coils found that older patients responded less well than younger ones. The explanation was anatomical: the cortex thins and the skull-to-brain distance grows with age, so a pulse calibrated at the motor cortex reached the prefrontal target with less strength. Some early protocols also used low intensities and short courses that would be considered underdosed today.

Deep TMS in patients 60 to 85

A 2018 randomized sham-controlled trial at the University of Toronto enrolled 52 patients aged 60 to 85 with treatment-resistant depression and gave them four weeks of daily Deep TMS or sham. Remission was 40 percent in the active group versus 14.8 percent with sham, a difference larger than in many trials of younger adults. The deeper reach of the H-coil was the proposed reason.

The FOUR-D trial

In 2022 the same group published the largest TMS trial in older adults: 172 patients aged 60 and up with treatment-resistant depression, randomized to theta burst stimulation or standard bilateral TMS, both at full intensity. Remission was about 35 percent with theta burst and 33 percent with standard treatment, confirming that older adults respond at rates comparable to younger patients when the dose is adequate.

StudyPatientsAgeRemission
Kaster 2018, Deep TMS vs sham5260 to 8540% vs 14.8%
Blumberger 2022, FOUR-D17260 and older35% theta burst, 33% standard
Carpenter 2012, naturalistic, all ages307Adults37%

What Medicare requires

There is no national coverage determination for TMS. Coverage is set by local coverage determinations issued by the Medicare administrative contractor for each region: First Coast Service Options for Florida and Palmetto GBA for South Carolina. Their requirements are similar.

  • Diagnosis: major depressive disorder, single or recurrent episode, documented with a standardized rating scale such as the PHQ-9, HAM-D or MADRS.
  • Medication history: failure of, or intolerance to, at least one antidepressant trial at an adequate dose and duration in the current episode. Intolerance counts, which matters for older adults who stopped a drug because of side effects.
  • Psychiatrist order: the treatment must be ordered by a psychiatrist after a face-to-face evaluation. A video visit can begin the process, but at least one in-person visit is required.
  • Course: an acute course of up to 30 daily sessions plus a taper, matching the standard 36-session protocol.
  • Retreatment: covered for patients who responded to a prior course and have relapsed.

Medicare Part B pays 80 percent of the allowed amount after the annual deductible. A Medigap supplement typically covers the remaining 20 percent, leaving little or no out-of-pocket cost. Medicare Advantage plans must cover what original Medicare covers but require prior authorization and may apply their own documentation rules. Our TMS coordinator verifies your specific plan before scheduling.

Safety with common conditions of aging

ConditionTMS statusWhat we do
Pacemaker or defibrillatorRelative contraindicationConfirm device model, obtain cardiology clearance; usually acceptable at chest distance
Prior strokeRelative contraindicationReview imaging and neurology notes; often proceed if no seizures and stroke is not recent
AnticoagulantsNo concernNothing to adjust; TMS does not affect bleeding
Diabetes, heart disease, kidney diseaseNo concernNo drug interactions; continue all medications
Hearing aidsNo concernRemoved during sessions; earplugs provided
Joint replacements, dental implants, stentsNo concernNon-ferromagnetic or far from the coil
Mild cognitive impairmentEvaluated individuallyProceed if able to sit for 20 minutes; treat the depression, not the dementia
Seizure historyRelative contraindicationNeurology records; often excluded if seizure within one year

Dosing differences in older patients

At the first session we find your motor threshold, the stimulation intensity that makes your thumb twitch, and set your treatment dose as a percentage above it. Older patients sometimes have a higher threshold because of cortical atrophy and because of medications that affect excitability, which simply means the dose is set higher. Deep TMS reaches further than surface coils, which is part of why the trials in older adults have done well. There is no reduction in dose for age; underdosing was the mistake of the early studies and we do not repeat it.

TMS for residents of senior living facilities

Our Stedfast Living program sends psychiatrists and psychiatric nurse practitioners into assisted living, independent living and skilled nursing facilities to provide ongoing care. Depression is common in these settings and often resistant to the limited medication options available to frail residents. When a resident may benefit from TMS, the evaluation can begin at the facility, the Medicare documentation is completed by the treating clinician, and we coordinate with facility staff on daily transportation to the Palm Beach Gardens treatment center for the six-week course. We keep the facility's nursing team informed of progress, side effects and any medication changes, and we involve family where the resident wishes. The daily schedule is a logistical commitment for a facility, and we plan it together before starting.

What families should know

A parent in their seventies or eighties starting TMS is not undertaking something risky or experimental. The treatment has nearly two decades of safety data, is covered by Medicare because it works, and has none of the sedation, confusion or fall risk that families worry about with psychiatric medication in older relatives. The commitment is time: a daily session for six weeks, then two a week for three more. Many families arrange a rotation of drivers or use a facility shuttle. You are welcome at the first session, and you will often notice improvement, in energy, in appetite, in willingness to engage, before your parent does.

Stedfast Psychiatry's TMS program begins with an evaluation at any of our 13 offices, by video, or at a senior living facility through Stedfast Living. Treatment sessions take place at our TMS treatment centers, with Palm Beach Gardens, 11641 Kew Gardens Ave, Suite 209, as the primary center. Call (561) 437-2199 to schedule a TMS evaluation or to ask our coordinator about Medicare coverage.

Frequently asked questions

Does TMS work as well for older adults?

Yes, in modern trials. Early studies with older coils and lower intensities found weaker results in seniors, which was attributed to age-related brain atrophy increasing the distance from coil to cortex. Deep TMS and higher-intensity protocols overcame that. A controlled trial of Deep TMS in patients aged 60 to 85 found remission in 40 percent versus about 15 percent with sham, and a 2022 trial of 172 older adults found remission in roughly a third with either of two standard protocols. Those rates match what younger adults achieve.

Does Medicare cover TMS?

Yes. Medicare Part B covers TMS for major depressive disorder in Florida and South Carolina under local coverage determinations. You need a documented diagnosis with a rating scale such as the PHQ-9, a record of at least one antidepressant trial that failed or could not be tolerated, and an in-person evaluation by a psychiatrist who orders the treatment. Medicare pays 80 percent after the deductible; a supplement plan usually covers the rest. Medicare Advantage plans cover it with prior authorization. Our coordinator handles the paperwork.

Can I have TMS with a pacemaker?

Usually, with cardiology clearance. The absolute contraindication is an electronic device within about 30 centimeters of the coil, which means implants in the head or neck such as cochlear implants and deep brain stimulators. A pacemaker or defibrillator in the chest is farther away and is typically acceptable once we confirm the device model and your cardiologist agrees. Bring your device card to the evaluation. Coronary stents, artificial heart valves and joint replacements are not a concern.

Is TMS safe after a stroke?

Often, with review. A stroke leaves scar tissue that can lower the seizure threshold, so we ask for your imaging and neurology records and consider how large and how old the stroke was. Many stroke survivors have received TMS safely, and post-stroke depression is common and undertreated. A recent stroke, a large cortical stroke or a history of post-stroke seizures may rule it out. The decision is made by the psychiatrist, sometimes in consultation with your neurologist.

Will TMS affect my memory?

No. TMS has no cognitive side effects, which is one of its main advantages over ECT in older adults. Several studies have found small improvements in attention, processing speed and memory after a TMS course, most likely because the depression that was impairing them has lifted. If memory problems are part of why you are seeking treatment, we evaluate whether they stem from depression, which improves with treatment, or from a separate cognitive disorder, which needs its own assessment.

I live in assisted living. How would I get to daily sessions?

Through our Stedfast Living program. Our clinicians already visit assisted living, independent living and skilled nursing facilities across our service area, and the TMS evaluation can begin there. If TMS is appropriate, we coordinate with the facility on transportation to our Palm Beach Gardens treatment center for the daily sessions, schedule a consistent time slot, and keep the facility's nursing staff informed of progress and any medication changes. Family members can be involved at every step.

Is TMS better than another antidepressant for someone my age?

After one or two failed trials, often yes. Each additional antidepressant has a lower chance of working, and in older adults each one adds risk: falls, low sodium, bleeding with blood thinners, confusion, interactions with heart and diabetes medications. TMS has none of those risks and response rates of 60 percent or higher in real-world registries. Most patients continue their current antidepressant during TMS rather than switching, which avoids a washout period. The decision depends on your history, and your psychiatrist will walk through it.

What if I have depression along with early dementia?

Depression and dementia often overlap, and depression can mimic or worsen cognitive decline. TMS treats the depression; it is not a treatment for dementia, despite what some advertising suggests. For a patient with mild cognitive impairment or early dementia and a clear depressive episode, TMS can be appropriate, and treating the depression sometimes improves thinking. The patient must be able to sit still for 20 minutes and tolerate the helmet and noise. We evaluate this individually, often with family input.

Where this treatment is offered

Conditions this treats

If you are in crisis, call or text 988 or go to the nearest emergency room. Educational content; individual results vary. Reviewed by Dr. David Husted, board-certified psychiatrist.

Talk to our TMS coordinator

Tell us how to reach you and our scheduling team will help you explore appointment options. Most new patients are seen within one to two weeks, in person or by video. Medicare and most plans accepted; self-pay new-patient visits are $185.